LOINC display name : Presumptive ABO group Molgen (Sal);
LOINC long common name : Presumptive ABO group [Type] in Saliva (oral fluid) by Molecular genetics method;
LOINC short name : ABO.presumptive Sal by Molgen;
LOINC description : The presumptive (predicted) ABO phenotype based on genetic analysis of the ABO gene.
Hematopoietic stem cell transplant donor registries often collect samples from potential
donors using buccal swabs or saliva as part of enrolling them in the registry. Because
these samples do not contain fresh intact red blood cells (RBCs) and traditional serological
ABO typing cannot be done, molecular typing is performed as part of the screening
process to find an appropriate hematopoietic stem cell donor. Prior to transfusion
or transplantation, the presumptive ABO result based on molecular typing must be confirmed
using traditional serologic typing. This term was created for, but not limited in
use to, the submitter's lab that performs sequence analysis of exons 6 and 7, at a
minimum, in the ABO gene and predicts the ABO phenotype from the resulting DNA sequence.;