HIV immunoassay testing algorithm interpretation:Imp:Pt:Ser/Plas/Bld:Nom: - CISMeF
HIV immunoassay testing algorithm interpretation:Imp:Pt:Ser/Plas/Bld:Nom:LOINC code
Preferred Label : HIV immunoassay testing algorithm interpretation:Imp:Pt:Ser/Plas/Bld:Nom:;
LOINC status : ACTIVE;
LOINC display name : HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp];
LOINC long common name : HIV immunoassay testing algorithm interpretation in Serum, Plasma or Blood;
LOINC short name : HIV IA algorithm interp SerPlBld-Imp;
LOINC description : This term is used to report the interpretation of results from an HIV immunoassay
testing algorithm that may be based on third, fourth, fifth and possibly other generations
of HIV immunoassays. HIV testing has evolved significantly in the past 30 years. The
first three generations of HIV immunoassays detected HIV antibodies (first IgG only,
then IgG and IgM). The fourth-generation tests can detect, but not differentiate between,
HIV-1 and HIV-2 antibodies as well as the HIV-1 p24 antigen. The inclusion of the
p24 antigen allows for detection of HIV as early as two weeks after exposure and before
seroconversion occurs (i.e. before antibodies are produced). In 2014, the U.S. Centers
for Disease Control and Prevention published a recommended algorithm for HIV diagnostic
testing based on fourth-generation HIV immunoassays [https://stacks.cdc.gov/view/cdc23447].
More recently, fifth-generation HIV immunoassays have been developed, which can detect
and differentiate between HIV-1 and HIV-2 antibodies and the HIV-1 p24 antigen. The
CDC is in the process of updating its testing algorithm and the latest information
can be found at https://www.cdc.gov/hiv/testing/laboratorytests.html. Note that third
generation assays are still available in the U.S. and earlier generations may also
be available outside the U.S.;