LOINC display name : B. pertussis bronchiseptica holmesii IS481 DNA NAA non-probe Ql (Nph);
LOINC long common name : Bordetella pertussis bronchiseptica holmesii IS481 DNA [Presence] in Nasopharynx by
NAA with non-probe detection;
LOINC short name : B pert bron holm IS481 Nph NAA non-Probe;
LOINC description : This test is primarily for the detection of the IS481 insertional element DNA of the
Bordetella pertussis genome in human nasopharyngeal swab samples taken from patients
suspected of having respiratory tract infection caused by B. pertussis. The IS481
insertion sequence can also be found in B. holmesii and B. bronchiseptica strains,
so respiratory infections with either Bordetella pertussis, B. holmesii or B. bronchiseptica
may yield positive test results in this assay, which does not differentiate between
these strains. Since B. pertussis and B. holmesii present with similar clinical symptoms,
additional testing would need to be performed to differentiate between these strains.
This term was created for, but not limited in use to, the illumigene Pertussis DNA
Amplification Assay, which uses loop-mediated isothermal DNA amplification (LAMP)
technology to detect the IS481 insertional element.;