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Programmed cell death ligand 1 by clone 28-8:PrThr:Pt:Tiss:Ord:Immune stain - CISMeF
Programmed cell death ligand 1 by clone 28-8:PrThr:Pt:Tiss:Ord:Immune stainLOINC code
Preferred Label : Programmed cell death ligand 1 by clone 28-8:PrThr:Pt:Tiss:Ord:Immune stain;
LOINC status : ACTIVE;
LOINC display name : PD-L1 by clone 28-8 Immune stain Ql (Tiss);
LOINC long common name : PD-L1 by clone 28-8 [Presence] in Tissue by Immune stain;
LOINC short name : PD-L1 by 28-8 Tiss Ql ImStn;
LOINC description : This term should be used to report the presence of PD-L1 (CD274) protein expression
in tumor cells as determined by immune staining with anti-PD-L1 clone 28-8. Patients
with certain cancers, such as non-squamous non small cell lung cancer (NSCLC) or melanoma,
whose tumors are positive for PD-L1 by 28-8 may be eligible for anti-programmed death
1 (PD-1) receptor antibody therapy, which effectively prevents the binding of PD-L1
to PD-1. The percentage of viable tumor cells that show partial or complete PD-L1
membrane staining is reported using [83053-9]. A tumor with 1% staining by 28-8
is considered PD-L1 positive. This term was created for, but is not limited in use
to, the Dako PD-L1 28-8 pharmDx test kit, which, as of November 2016, is FDA-approved
as a companion diagnostic to assess whether patients with certain cancers are eligible
for nivolumab therapy.;
Has component