LOINC display name : Pediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS)
panel (S);
LOINC long common name : Pediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS)
panel - Serum;
LOINC short name : PANDAS panel Ser;
LOINC description : PANDAS (pediatric autoimmune neuropsychiatric disorder associated with streptococcus
infection) is a condition in which some children experience a sudden onset or worsening
of neuropsychiatric symptoms, such as OCD and tics, following a group A streptococcus
infection. There is correlational evidence that PANDAS may be triggered by an autoimmune
response to the streptococcus infection. The anti-dopamine, anti-lysoganglioside,
and anti-beta tubulin antibodies produced by the immune system in response to the
streptococcus infection is associated with higher activation of CaM-Kinase II, which
may disrupt neurologic activity in the basal ganglia.[NCBI Books:NBK333433][PMID:12204920];
Has component