LOINC display name : Gadolinium (Tiss) [Mass/Mass];
LOINC long common name : Gadolinium [Mass/mass] in Tissue;
LOINC short name : Gadolinium Tiss-mCnt;
LOINC description : Due to its paramagnetic properties, chelated gadolinium is commonly employed as contrast
media for magnetic resonance imaging (MRI) and computer tomography (CT) scanning.
Gadolinium is eliminated primarily by the renal filtration. In healthy subjects with
normal renal function, the plasma half-life of gadolinium is approximately 90 minutes.
Patients with reduced renal function exhibit increased gadolinium excretion half-life
and may be affected by nephrogenic systemic fibrosis (NSF). In this syndrome, prolonged
retention of gadolinium is thought to allow the gadolinium cation to dissociate from
its synthetic organic chelator and deposit predominantly in the skin, although other
organs may be affected as well. These patients are often severely debilitated by progressive
skin thickening and tightening. Fibrosis of skeletal muscle, lungs, liver, testes,
and myocardium have also been observed, often with fatal results. Three hemodialysis
treatments are required to substantially remove gadolinium from patients with impaired
renal function; peritoneal dialysis is not effective.;
Has component