LOINC display name : ZIKV neut ab spec 2 Neut test (CSF) [Titer];
LOINC long common name : Zika virus neutralizing antibody [Titer] in Cerebral spinal fluid by Neutralization
test --2nd specimen;
LOINC short name : ZIKV NAb sp2 Titr CSF Nt;
LOINC description : Quantitative result for Zika virus neutralizing antibodies in a convalescent phase
CSF sample. Serological cross-reactivity is strong between Zika and other flaviviruses,
especially Dengue virus. Therefore, positive EIA or IF assays for Zika virus IgM antibodies
are presumptive only and should be confirmed by a neutralization assay, such as the
plaque-reduction neutralization test (PRNT), which can discriminate between Zika virus
and cross-reacting antibodies in primary flavivirus infections. Recent Zika virus
infection is confirmed by stable high neutralizing antibody titers, seroconversion,
or a 4x or greater increases in neutralizing antibody titer in a patient's appropriately
timed acute and convalescent phase specimens.;
Has challenge