LOINC display name : ZIKV neut ab spec 2 Neut test (S) [Titer];
LOINC long common name : Zika virus neutralizing antibody [Titer] in Serum by Neutralization test --2nd specimen;
LOINC short name : ZIKV NAb sp2 Titr Ser Nt;
LOINC description : Quantitative result for Zika virus neutralizing antibodies in convalescent phase serum.
Serological cross-reactivity is strong between Zika and other flaviviruses, especially
Dengue virus. Therefore, positive EIA or IF assays for Zika virus IgM antibodies are
presumptive only and should be confirmed by a neutralization assay, such as the plaque-reduction
neutralization test (PRNT), which can discriminate between Zika virus and cross-reacting
antibodies in primary flavivirus infections. Recent Zika virus infection is confirmed
by stable high neutralizing antibody titers, seroconversion, or a 4x or greater increases
in neutralizing antibody titer in a patient's appropriately timed acute and convalescent
phase sera.;
Has challenge