LOINC long common name : Zika virus IgM Ab [Units/volume] in Cerebral spinal fluid by Immunoassay;
LOINC short name : ZIKV IgM CSF IA-aCnc;
LOINC description : Quantitative analysis of Zika virus IgM antibodies in cerebral spinal fluid (CSF)
specimens by immunoassay-based methods. Similar to most EIA tests, results are reported
as a ratio of optical densities. Zika virus IgM antibodies become detectable 4-8 days
after the onset of symptoms and persist for months. Since IgM does not normally cross
the blood-brain barrier, detection of Zika virus IgM in CSF implies CNS infection.
Serological cross-reactivity is strong between Zika and other flaviviruses, especially
Dengue virus. Therefore, positive results for this test are presumptive and should
be confirmed by neutralizing antibody testing [LOINC: 80621-6]. Negative results for
this test on a sample taken during the first week of illness does not rule out infection
and the test should be repeated on a convalescent sample.;
Has component