LOINC display name : B. pertussis and B. parapertussis panel (Nph);
LOINC long common name : Bordetella pertussis and Bordetella parapertussis DNA and culture panel - Nasopharynx;
LOINC short name : B pert parapert DNA cult Pnl Nph;
LOINC description : Pertussis is an acute infectious disease caused by the bacterium Bordetella pertussis.
PCR has increased sensitivity and faster results reporting, however culture is still
considered the gold standard laboratory test and the most specific laboratory test
for pertussis. PCR is done to detect the presence of a repetitive insertion sequence
IS481 that has been specifically found to be present in up to 100 copies within the
genome of B. pertussis. 8-10 copies of this insertion sequence can also be found in
B. holmesii however. On rare occasion, a copy of this sequence is also found in B.
bronchiseptica, thus these two species may test positive for the PCR assay. Concurrent
culturing is used to differentiate these two species from B. pertussis and confirm
the organism, while PCR allows preliminary results to be reported the same day that
the specimen is received.;