Preferred Label : Liver fibrosis score:Score:Pt:Ser/Plas:Qn:Calculated.HepaScore;
LOINC status : ACTIVE;
LOINC display name : Liver fibrosis score Calculated by HepaScore [Score];
LOINC long common name : Liver fibrosis score in Serum or Plasma Calculated by HepaScore;
LOINC short name : Liver fibr score SerPl Calc HepaScore;
LOINC description : This term was created for the HepaScore liver fibrosis test, which is a marker of
liver fibrosis in patients with hepatitis C infection. The score ranges from 0 to
1 and is calculated based on four lab tests (GGT, bilirubin, alpha-2-macroglobulin,
and hyaluronic acid) plus the patient's age and gender. The HepaScore is reported
with a central cut-off of 0.50, with a value 0.50 indicating that significant liver
fibrosis is present (positive predictive value 88%) and a value 0.50 indicating
that advanced fibrosis is absent (negative predictive value 95%) for patients with
hepatitis C infection. The HepaScore logistic regression model is as follows: y
exp[-4.185818 - (0.0249 x age) (0.7464 x sex) (1.0039 x α2-macroglobulin) (0.0302
x hyaluronic acid) (0.0691 x bilirubin) - (0.0012 x GGT)] with age provided in years,
male sex 1, female sex 0, α2-macroglobulin in g/L, hyaluronate in μg/L, bilirubin
in μmol/L, and GGT in U/L. The score itself is calculated as y/(1 y). [PMID: 16055434];
Origin ID : 78894-3;
UMLS CUI : C4070622;
Has component
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- Has property
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- Has time aspect
- Part of panel
- Semantic type(s)
