LOINC long common name : Platelet aggregation adenosine diphosphate prostaglandin E1 induced [Units/volume]
in Blood;
LOINC short name : PA ADP PGE1 induced Bld-aCnc;
LOINC description : Quantitative in vitro determination of platelet function in whole blood triggered
by the addition of adenosine diphosphate (ADP) and prostaglandin E1 (PGE1). ADP induces
platelet aggregation by two pathways mediated by the platelet receptors P2Y1 and P2Y12,
respectively. The addition of PGE1 inhibits the P2Y1 activation pathway, which enables
more specific evaluation of substances, such as clopidogrel, that affect platelet
aggregation through the P2Y12 pathway. This term was created for, but not limited
in use to, the Cobas Prostaglandin E1 Reagent used in conjunction with the ADPtest.
The combination of the two is also known as ADPtest High Sensitivity (HS) assay.;