Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate:CRto:Pt:Fibroblasts:Qn:

Preferred Label : Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate:CRto:Pt:Fibroblasts:Qn:;

LOINC status : ACTIVE;

LOINC display name : Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate (Fibroblast) [Catalytic ratio];

LOINC long common name : Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate [Enzymatic activity ratio] in Fibroblast;

LOINC short name : ACADs.palmitate/ACADs.myristate Fib-cRto;

LOINC description : Medium- and long-chain acyl CoA dehydrogenase deficiencies can be differentiated based on the ratio of palmitate oxidation [LOINC: 78358-9] and myristate oxidation [LOINC: 78360-5] in cultured fibroblasts. Patients with medium chain acyl-CoA dehydrogenase deficiency (MCAD) typically have a high palmitate/myristate (P/M) ratio. Long-chain defects, including VLCAD and LCHAD, generally have a low P/M ratio. [PMID: 10709659];

Details

Origin ID

78359-7;

UMLS CUI

C4071115;

Has component
- Acyl CoA dehydrogenases [LOINC component]
- Acyl CoA dehydrogenases.palmitate substrate [LOINC component]
- Acyl CoA dehydrogenases.palmitate substrate/Acyl CoA dehydrogenases.myristate substrate [LOINC component]
- Myristate (C14:0) [LOINC component]
- Palmitate (C16:0) [LOINC component]
Has property
- Catalytic Ratio [LOINC Property]
Has system
- Fibroblast [LOINC System]
Has time aspect
- Point in time (spot) [LOINC time aspect]
Part of panel
- Fatty acid oxidation panel:-:Pt:Fibroblasts:-: [LOINC code]
Semantic type(s)
- Clinical Attribute [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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