LOINC display name : Natriuretic peptide.B prohormone N-Terminal IA (Pleur fld) [Mass/Vol];
LOINC long common name : Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay;
LOINC short name : NT-proBNP Plr IA-mCnc;
LOINC description : Brain natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) are significantly
elevated in patients with heart failure because tension or stretching of the cardiac
wall, such as occurs with heart failure, stimulates the synthesis of natriuretic peptides.
Pleural fluid BNP and NT-proBNP is a useful biomarker for pleural effusions secondary
to heart failure. A pleural NT-proBNP cutoff value of 1,165 pg/mL had a sensitivity
of approximately 95% for discriminating heart failure-related effusions from exudates,
and a cutoff of 2,300 pg/mL had a sensitivity of approximately 70% for discriminating
heart failure-related transudates from non-heart-failure related pleural effusions.
[PMID: 22710710] This term was created for, but is not restricted in use to, the Elecsys
proBNP II assay, which contains two monoclonal antibodies that recognize epitopes
located in the N-terminal part (1-76) of proBNP (1-108).;
Has method