Preferred Label : Salivary gland protein 1 & Carbonic anhydrase 6 & Parotid secretory protein Ab.IgA
& IgG & IgM panel:-:Pt:Ser:Qn:IA;
LOINC status : ACTIVE;
LOINC display name : Salivary gland protein 1 and Carbonic anhydrase 6 and Parotid secretory protein IgA
and IgG and IgM panel IA (S);
LOINC long common name : Salivary gland protein 1 and Carbonic anhydrase 6 and Parotid secretory protein IgA
and IgG and IgM panel - Serum by Immunoassay;
LOINC short name : SP-1 CA6 PSP IgA IgG IgM Pnl Ser IA;
LOINC description : Sjogren's disease is an autoimmune disease associated with kidney and lung disease
as well as disorders of the salivary and lacrimal glands, which lead to problems with
dry eyes and mouth. Sjogren's syndrome is associated with isolated salivary and lacrimal
gland dysfunction and may be associated with other autoimmune disorders, such as systemic
lupus erythematosus. Antibodies to salivary gland protein 1 (SP-1), carbonic anhydrase
6 (CA6) and parotid secretory protein (PSP) may be useful markers for identifying
patients with Sjogren's disease or Sjogren's syndrome early in the course of disease
and for those who have significant symptoms but are anti-Ro and anti-La antibody negative,
which are two of the antibodies that are typically used to diagnose Sjogren's. Antibodies
to SP-1, CA6 and PSP rarely occur in healthy controls or patients with other autoimmune
disorders who do not have eye and mouth symptoms. [PMID: 23123440] This term was created
for, but is not limited in use to, the IMMCO Diagnostics' early Sjogren's syndrome
antibody profile, which includes terms for IgA, IgG and IgM antibodies to SP-1, CA6
and PSP.;
Origin ID : 77217-8;
UMLS CUI : C4037106;
Has component
- Has method
- Has system
- Has time aspect
- Panel of LOINC codes
- Semantic type(s)
