" /> Hepatocyte growth factor receptor Ag:PrThr:Pt:Tiss:Ord:Immune stain - CISMeF





Preferred Label : Hepatocyte growth factor receptor Ag:PrThr:Pt:Tiss:Ord:Immune stain;

LOINC status : ACTIVE;

LOINC display name : Hepatocyte growth factor receptor Ag Immune stain Ql (Tiss);

LOINC long common name : Hepatocyte growth factor receptor Ag [Presence] in Tissue by Immune stain;

LOINC short name : HGFR Ag Tiss Ql ImStn;

LOINC description : The stain is interpreted as positive if 50% or more of the tumor cells show moderate to strong (2 , 3 ) membranous staining, indicating MET amplification. MET amplification (positive) has been seen in approximately 22% of non-small-cell lung cases with acquired resistance to anti-EGFR inhibitors. Recent Phase II clinical trails (OAM4558g) results were released at ASCO in 2011 showed that patients who were c-MET positive (2 or 3 ) lived twice as long without disease progression (PFS) when they received MetMAb therapy in combination with erlotinib versus receiving erlotinib alone.;

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28/05/2025


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