LOINC long common name : Human papilloma virus 18 45 E6 E7 mRNA [Presence] in Cervix by NAA with probe detection;
LOINC short name : HPV18 45 E6 E7 mRNA Cvx Ql NAA probe;
LOINC description : Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 18 and
45 in cervical specimens from women with positive HPV assay results. E6/E7 oncogenes
must be expressed for malignant transformation. For women 21-years and older with
atypical squamous cells of undetermined significance (ASC-US) cervical cytology results,
and HPV positive assay results, this assay can be used to assess the presence or absence
of high-risk HPV genotypes 18, and/or 45. For women 30-years and older, the HPV 18,
and/or 45 genotype assay can be used to test samples from women with HPV assay positive
results, along with cervical cytology results. This assay has not been evaluated for
HPV vaccinated patients or in cases of suspected abuse. It does not differentiate
HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima
HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated
amplification and detection of the amplification products by hybridization protection.
To report results for HPV 16 see Human papilloma virus 16 E6 E7 mRNA [Presence] in
Cervix by Probe and signal amplification method [LOINC: 82456-5].;