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Lupus anticoagulant two screening tests W Reflex panel:-:Pt:PPP:-:Coag - CISMeF
Lupus anticoagulant two screening tests W Reflex panel:-:Pt:PPP:-:CoagLOINC code
Preferred Label : Lupus anticoagulant two screening tests W Reflex panel:-:Pt:PPP:-:Coag;
LOINC status : ACTIVE;
LOINC display name : Lupus anticoagulant two screening tests W Reflex panel Coag (PPP);
LOINC long common name : Lupus anticoagulant aPTT and dRVVT screening panel W Reflex;
LOINC short name : LA aPTT dRVVT screen W reflex panel;
LOINC description : The development of this panel for detecting Lupus Anticoagulant (LA) was shaped by
the 2009 International Society of Thrombosis and Haemostasis (ISTH) and 2014 Clinical
and Laboratory Standards Institute (CLSI) guidelines for lupus anticoagulant testing.
They both recommend using two separate coagulation tests and identify dRVVT and aPPT
as the two best choices. This aPPT & dRVVT panel is most closely aligned with the
ISTH guidelines. The testing cascade starts with the use of the two above-named tests
to screen for or verify a clotting abnormality, and if either is abnormal, reflexing
to the same test with 1:1 pooled plasma (to exclude clotting factor deficiencies)
and again with excess phospholipid (PL). Correction of the coagulopathy with excess
phospholipid confirms the likelihood of LA. Neither published guidance nor laboratories
agree on the order in which the two kinds of reflex tests should be done, and this
panel does not take a position on that subject. Some laboratories report the absolute
values of the test and some the normalized ratios. So LOINC includes both as alternatives.
Only one or the other of the alternatives must be included in the panel report. A
summary interpretation is required by both guidelines.;
Has component