LOINC display name : MAML2 11q21 rearrangements FISH Doc (Tiss);
LOINC long common name : MAML2 11q21 gene rearrangements in Tissue by FISH;
LOINC short name : MAML2 11q21 Tiss FISH;
LOINC description : Rearrangements within the MAML2 gene located on chromosome 11q21 are detected in tissue
(e.g. salivary gland tumors) by in-situ hybridization (e.g. FISH) methods. Presence
of split signals indicate gene rearrangement. MAML2 rearrangements must be present
in greater than or equal to 10% of lesional cells in order to be considered positive.
The submitter's lab for this term report results (e.g. percent of lesional cells,
ISCN nomenclature, and qualification of a positive result) as descriptive text. For
example, a narrative result may state, 50% of lesional cells contain MAML2 rearrangement,
nuc ish(MAML2x2)(5MAML2 sep 3MAML2x1)[100/200]. MAML2 rearrangement must be present
in greater than or equal to 10% of lesional cells in order to be considered positive.
Results are used to diagnose Mucoepidermoid carcinoma (MEC). Other carcinomas, such
as salivary duct carcinoma, adenosquamous carcinoma, acinic cell carcinoma, and Warthin
tumor are negative for the MAML2 rearrangements.;
Has component