von Willebrand factor.activity:ACnc:Pt:PPP:Qn:IA - CISMeF
Von Willebrand factor.activity:ACnc:Pt:PPP:Qn:IALOINC code
Preferred Label : von Willebrand factor.activity:ACnc:Pt:PPP:Qn:IA;
LOINC status : ACTIVE;
LOINC display name : vWf.activity IA Qn (PPP);
LOINC long common name : von Willebrand factor (vWf).activity [Units/volume] in Platelet poor plasma by Immunoassay;
LOINC short name : vWf:Ac PPP IA-aCnc;
LOINC description : Von Willebrand Factor Activity (VWF Activity, vWF:Act) in plasma specimens can be
quantitatively determined by immunological methods. This code is created for, but
not limited in use to, the submitter's kit, HemosIL Von Willebrand Factor Activity
Kit, which determines VWF activity by measuring the increase of turbidity produced
by the agglutination of the latex reagent. This assay uses a specific anti-VWF monoclonal
antibody directed against the platelet binding site of VWF, glycoprotein Ib receptor,
and reacts with the VWF in patient plasma. The degree of agglutination is directly
proportional to the activity of VWF in the sample and is determined by measuring the
decrease of transmitted light caused by the aggregates. The submitter's lab reports
the results in U/mL where U represents units rather than the standard meaning of U,
which is mmol/Min, a measure of enzyme rates. Additional testing (e.g. ristocetin
cofactor assay) may be needed to confirm a diagnosis of von Willebrand disease (VWD).;