LOINC display name : HIV reverse transcriptase protease integrase gene mutations detected Nom (Isol);
LOINC long common name : Deprecated HIV reverse transcriptase protease integrase gene mutations detected [Identifier];
LOINC short name : Deprecated HIV RT PR IN Mut Det Islt;
LOINC description : HIV-1 genotyping resistance assay starts with the isolation of HIV-1 RNA from blood
plasma, followed by amplification of the protease (PR), reverse transcriptase (RT)
and integrase (IT) coding regions using sequencing methods to determine drug susceptibility.
This code is based on, but not limited in use to, the submitter's test kit (GenoSure
PRIme),a DNA sequence assay that detects mutations within the protease (amino acids
1-99), reverse transciptase (amino acids 1-400), and integrase (amino acids 1-288)
coding regions of HIV-1. Assessment of drug susceptibility is based on the interpretation
of mutations identified. It is performed to assess treatment failure, assist in choosing
alternate regimens, and to assist in choosing a regimen that will reduce vertical
transmission in pregnant HIV infected women. The answer list provided with this code
represents example mutations that may be identified and is not a complete list.;
Has component