LOINC long common name : NPM1 gene c.960insCCTG transcript/control transcript [# Ratio] in Bone marrow by Molecular
genetics method;
LOINC short name : NPM1 gene mut D/control Mar;
LOINC description : The quantification of NPM1 mutation D (c.960insCCTG) transcripts are compared to a
control gene (e.g. ABL1) by real-time PCR (RT-qPCR). NPM1 primers and probes spanning
exons 11 and 12 may be used to detect quantify the NPM1 mutation transcripts. Results
are based on the normalized copy number [NPM1 mut D copy number/ABL1 copy number)
x 100]. This test is based on, but not limited to, IPSOGEN'S NPM1-B/D MutaQuant Kit,
which is used as research tool (as of 2012) for the quantification of NPM1-D transcripts
in samples previously identified as carrying the NPM1 mutation D. The results are
used to monitor the decrease of NPM1 mutD expression.;
Has component