LOINC long common name : NPM1 gene c.956dupTCTG transcript/control transcript [# Ratio] in Bone marrow by Molecular
genetics method;
LOINC short name : NPM1 gene mut A/control Mar;
LOINC description : The quantification of NPM1 mutation A (c.956dupTCTG) transcripts are compared to a
control gene (e.g. ABL1) by real-time PCR (RT-qPCR). NPM1 primers and probes spanning
exons 11 and 12 may be used to detect quantify the NPM1 mutation transcripts. Results
are based on the normalized copy number [NPM1 mut A copy number/ABL1 copy number)
x 100]. This test is based on, but not limited to, IPSOGEN'S NPM1-A MutaQuant Kit,
which is used as research tool (as of 2012) for the quantification of NPM1 transcripts
in samples previously identified as carrying the NPM1 mutation A. The results are
used to monitor the decrease of NPM1 mutA expression.;
Has component