inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript:NRto:Pt:Bld/Tiss:Qn:Molgen

Preferred Label : inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript:NRto:Pt:Bld/Tiss:Qn:Molgen;

LOINC status : ACTIVE;

LOINC display name : inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio];

LOINC long common name : inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method;

LOINC short name : inv(16)(p13;q22)/control Bld/T;

LOINC description : A pericentric inversion of chromosome 16, inv(16)(p13;q22), results in a fused transcript between MYH11 (16p13.1) and CBFB (16q22.1) genes and is known to cause acute myeloid leukemia (AML). Techniques like real-time PCR are used to detect the MYH11-CBFB fused transcript. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.;

Détails

Origin ID

72210-8;

UMLS CUI

C3533815;

Has component
- inv(16)(p13.1;q22.1)(MYH11,CBFB) [LOINC component]
- inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript [LOINC component]
Has method
- Molecular genetics [LOINC method]
Has property
- Number Ratio [LOINC Property]
Has system
- Blood [LOINC System]
- Blood or Tissue [LOINC System]
- Tissue and Smears [LOINC System]
Has time aspect
- Point in time (spot) [LOINC time aspect]
Part of panel
- Acute & chronic leukemia fusion transcript per control transcript panel:-:Pt:Bld/Tiss:-:Molgen [LOINC code]
Semantic type(s)
- Clinical Attribute [UMLS semantic type]

Position du mot-clé dans l'(les) arborescence(s) :

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