LOINC display name : HPV E6 E7 mRNA cells/cells FC Ql (Cvx);
LOINC long common name : HPV E6 E7 mRNA cells/cells [Presence] in Cervix by Flow cytometry (FC);
LOINC short name : HPV E6 E7 mRNA cells/cells Cvx Ql FC;
LOINC description : This term was created for an assay that identifies cervical cells containing HPV E6
and E7 polycistronic mRNA using in situ hybridization with oligonucleotides specific
for the mRNA transcripts. The cells remain intact, and following fixation and permeabilization,
the probes enter the cells. The flow cytometer measures two things: 1. Quantification
of E6 and E7 mRNA in each cell and 2. The percentage of cells over-expressing E6 and
E7 mRNA. The test does not report the percentage quantity but an ordinal (positive,
negative, indeterminant) based on the reported percentage. This test is similar to
LOINC 69002-4, which is a target amplification nucleic acid probe test to detect E6
E7 mRNA.;