Preferred Label : Human papilloma virus 16 18 31 33 35 39 45 51 52 56 58 59 66 68 E6 E7 mRNA:PrThr:Pt:Cvx:Ord:Probe.amp.tar;
LOINC status : ACTIVE;
LOINC display name : HPV E6 E7 mRNA NAA probe Ql (Cvx);
LOINC long common name : Human papilloma virus E6 E7 mRNA [Presence] in Cervix by NAA with probe detection;
LOINC short name : HPV E6 E7 mRNA Cvx Ql NAA probe;
LOINC description : This term was created for (but not limited to) Gen-Probe's Aptima HPV assay (Cat No.
302610) that detects the E6 and E7 polycistronic mRNA from 14 high-risk HPV genotypes
(16,18,31,33,35,39,45,51,52,56,58,59,66,and 68) that can lead to cervical cancer.
E6/E7 genes in high-risk HPV genotypes are known as oncogenes because of their continuous
expression, which leads to disruption of cell-cycle check points and cell genome instability
through alteration of cellular p53 and retinoblastoma protein functions. This test
is similar to LOINC 69358-0, which measures cells containing E6 E7 mRNA via flow cytometry.;
Origin ID : 69002-4;
UMLS CUI : C3262836;
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