" /> Skin Ab.IgG:PrThr:Pt:Ser:Ord:Monkey esophagus substrate - CISMeF





Preferred Label : Skin Ab.IgG:PrThr:Pt:Ser:Ord:Monkey esophagus substrate;

LOINC status : ACTIVE;

LOINC display name : Skin IgG Monkey esophagus substrate Ql (S);

LOINC long common name : Skin IgG Ab [Presence] in Serum by Monkey esophagus substrate;

LOINC short name : Skin IgG Ser Ql Monkey esoph;

LOINC description : The detection of skin antibodies assists in the diagnosis of chronic vesicular-bullous diseases such as pemphigus and pemphigoid. When patient sera are incubated on monkey or guinea pig esophagus sections, anti-skin antibodies present in the serum will bind with disease-specific patterns by immunofluorescence. For example, the intercellular (IC) antibody pattern diagnoses pemphigus with a 90% sensitivity. Testing with the 2 different species of esophagus sections (monkey and guinea pig) assists in distinguishing different forms of pemphigus. Antibodies following a basement membrane pattern are present in bullous pemphigoid (70%), vesicular pemphigoid (50%) and cicatricial pemphigoid (10%).;

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04/05/2025


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