LOINC display name : Skin Ab.IgG pattern Monkey esophagus substrate (S) [Interp];
LOINC long common name : Skin Ab.IgG pattern [Interpretation] in Serum by Monkey esophagus substrate;
LOINC short name : Skin Ab.IgG pattern Ser Monkey esoph-Imp;
LOINC description : The detection of skin antibodies assists in the diagnosis of chronic vesicular-bullous
diseases such as pemphigus and pemphigoid. When patient sera are incubated on monkey
or guinea pig esophagus sections, anti-skin antibodies present in the serum will bind
with disease-specific patterns by immunofluorescence. For example, the intercellular
(IC) antibody pattern diagnoses pemphigus with a 90% sensitivity. Testing with the
2 different species of esophagus sections (monkey and guinea pig) assists in distinguishing
different forms of pemphigus. Antibodies following a basement membrane pattern are
present in bullous pemphigoid (70%), vesicular pemphigoid (50%) and cicatricial pemphigoid
(10%).;
Has component