LOINC long common name : Skin Ab [Titer] in Serum;
LOINC short name : Skin Ab Titr Ser;
LOINC description : The detection of skin antibodies assists in the diagnosis of chronic vesicular-bullous
diseases such as pemphigus and pemphigoid. When patient sera are incubated on monkey
or guinea pig esophagus sections, anti-skin antibodies present in the serum will bind
with disease-specific patterns by immunofluorescence. For example, the intercellular
(IC) antibody pattern diagnoses pemphigus with a 90% sensitivity. Testing with the
2 different species of esophagus sections (monkey and guinea pig) assists in distinguishing
different forms of pemphigus. Antibodies following a basement membrane pattern are
present in bullous pemphigoid (70%), vesicular pemphigoid (50%) and cicatricial pemphigoid
(10%).;
Has component