LOINC display name : T-cell subsets CD4 and CD8 panel (Bld);
LOINC long common name : T-cell subsets CD4 and CD8 panel - Blood;
LOINC short name : T-cell subsets CD4 CD8 pnl Bld;
LOINC description : In this test panel both CD3 and CD4 are required to recognize CD4 T cells (helper
cells), and both CD3 and CD8 to recognize CD8 T cells (suppressor cells). The measurement
of Helper T-cell levels has been used to establish decision points for initiating
P. jiroveci prophylaxis, antiviral therapy and to monitor the efficacy of treatment.
The Public Health Service (PHS) has recommended that Helper T-cell levels be monitored
every three to six months in all HIV-infected persons. During HIV infection, antiviral
therapy is often initiated when the absolute CD4 T cell count drops below 500 cells/µL.
When the absolute CD4 T cell count drops below 200 cells/µL, therapeutic prophylaxis
against PCP and other opportunistic infections may be initiated. When the absolute
CD4 T cell count drops below 100 cells/µL, prophylaxis against Mycobacterium avium
complex is recommended. (from ARUP, modified);
Has component