Preferred Label : PhenX - spine - femur bone density by dual-energy x-ray absorptiometry protocol 170701:-:Pt:
Patient:-:PhenX;
LOINC status : TRIAL;
LOINC long common name : PhenX - spine - femur bone density by dual-energy x-ray absorptiometry protocol 170701;
LOINC short name : Spine - femur bone density DXA proto;
LOINC description : The Framingham Osteoporosis Study Generation 3 Musculoskeletal Exam includes instructions
for preparing the sample person for the scan, performing quality assurance procedures,
and performing the scan of the hip and spine. Given that there are multiple manufacturers
and models of dual-energy X-ray absorptiometry (DXA) machines (each with associated
software), investigators must report the equipment they are using and cannot directly
compare bone density measurements from different DXA machines (per the International
Society for Clinical Densitometry (2007) and Bonnick, S. L. (2009)). Additionally,
weekly scans using DXA phantoms are recommended as an independent assessment of system
calibration. Studies that use more than one DXA machine should also implement a plan
to monitor inter-scanner differences at baseline and at regular intervals during the
study. Additionally, for studies involving more than one technician, an average precision
error that combines data from all of the technicians should be used to establish the
least significant change (LSC) and the precision error for the DXA facility (per the
International Society for Clinical Densitometry (2007)). Lastly, the precision error
for technicians should be evaluated periodically, such as after they have received
training on the specific DXA machine, have completed DXA scans on about 100 patients,
if there has been a change in their skill level, or if a new DXA system is used (per
the International Society for Clinical Densitometry (2007)). Note: Manufacturers of
DXA equipment are constantly striving to improve and update both their equipment and
software with the latest technological advances. Hence, please refer to the DXA specifications
for your model number to ensure that the level of information collected is compatible
with the PhenX protocol. Given that the selected protocol uses a GE Lunar densitometer(c),
the PhenX Skin, Bone, Muscle and Joint Working Group recommends that users of HologicTM
densitometers find comparable protocols used by the National Health and Nutrition
Examination Survey (NHANES). DXA measurement is complex and requires costly hardware,
specialized software to analyze the DXA scans, rigorous quality control, specialized
examiners, continuous equipment calibration and monitoring, and scan quality control
monitoring. Although excerpts of the procedure manual for the Framingham Osteoporosis
Study Generation 3 Musculoskeletal Exam (May 2008-2010) protocol are provided for
informational purposes, investigators should review all facets of the protocol prior
to undertaking DXA examinations in a study.;
Origin ID : 62910-5;
UMLS CUI : C3171910;
Has component
- Has method
- Has system
- Has time aspect
- Panel of LOINC codes
- Part of panel
- Semantic type(s)
