LOINC long common name : Deprecated PhenX measure - fasting serum insulin;
LOINC description : A bioassay to measure serum concentration of insulin, a hormone produced by pancreatic
beta cells that regulates the body's ability to metabolize glucose. Concentrations
of serum insulin may help distinguish between type 1 and type 2 diabetes. Type 1,
or insulin-dependent, diabetes is characterized by autoimmune destruction of the pancreas
and eventually leads to absolute insulin deficiency and very low or no circulating
insulin. Type 2, or non insulin-dependent, diabetes is characterized by insulin resistance
and subjects initially have much higher circulating insulin concentrations. This may
be followed by decreasing insulin levels due to pancreatic beta cell exhaustion (American
Diabetes Association, 2010). Further, fasting serum insulin alone or combined with
fasting plasma glucose can be used as a surrogate estimate of insulin resistance and
beta-cell function.;
Has component