T-cell receptor excision circle:NCnc:Pt:Bld.dot:Qn:Probe.amp.tar

Preferred Label : T-cell receptor excision circle:NCnc:Pt:Bld.dot:Qn:Probe.amp.tar;

LOINC status : ACTIVE;

LOINC display name : T-cell receptor excision circle NAA probe (DBS) [#/Vol];

LOINC long common name : T-cell receptor excision circle [#/volume] in DBS by NAA with probe detection;

LOINC short name : TREC # DBS NAA probe;

LOINC description : In newborn screening laboratories where dried blood spots (DBS) are the only available specimens, the test for T cell receptor excision circles (TREC) has been established as a reliable method in population-based pilot studies. TRECs are circular episomal DNA generated at the rearrangement of T cell antigen-receptor gene segments during maturation of T lymphocytes in the thymus. They are non-replicating byproducts that stay in the recent thymic emigrants in the peripheral blood. As such, they can serve as sensitive markers of T cell production in the newborn infant.;

Details

Origin ID

62320-7;

UMLS CUI

C2973228;

Has component
- T-cell [LOINC component]
- T-cell receptor excision circle [LOINC component]
Has method
- Nucleic acid amplification with probe detection [LOINC method]
- Probe [LOINC method]
- Probe with amplification [LOINC method]
Has property
- Number Concentration [LOINC Property]
Has system
- Blood [LOINC System]
- DBS [LOINC System]
Has time aspect
- Point in time (spot) [LOINC time aspect]
Part of panel
- Severe combined immunodeficiency (SCID) newborn screening panel:-:Pt:Bld.dot:-: [LOINC code]
Semantic type(s)
- Clinical Attribute [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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