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HLA-A B C SBT:Imp:Pt:Bld/Tiss:Nom:High resolution - CISMeF
HLA-A B C SBT:Imp:Pt:Bld/Tiss:Nom:High resolutionLOINC code
Preferred Label : HLA-A B C SBT:Imp:Pt:Bld/Tiss:Nom:High resolution;
LOINC status : ACTIVE;
LOINC display name : HLA-A B C SBT High resolution (Bld/Tiss) [Interp];
LOINC long common name : HLA-A B C SBT [Interpretation] by High resolution;
LOINC short name : HLA-A B C SBT High Res-Imp;
LOINC description : HLA-ABC sequence based typing results in HLA allele assignment for each HLA locus(A,B,C).
HLA antigens are the major histocompatibility antigens. HLA Class 1 Sequence-Based
typing (HLA-SBT) is used to identify HLA allelic polymorphisms at the level of individual
nucleotides using genomic DNA amplified by polymerase chain reaction(PCR). If fewer
than two alleles are reported for a locus, the patient can most likely be considered
homozygous for that locus, but there is a possibility of an undetected rare allele.
HLA-SBT should be used in addition to HLA Class 1 serology and/or low to intermediate
resolution molecular typing using either SSP(sequence-specific primers) or SSOPH(sequence-specific
oligonucleotide blot hydridization) technology. For clinical purposes, this test should
be used as a reflex test to identify unrelated bone marrow donors who are HLA A,B,
and C genotypic matches with the intended recipient.;
Has method