LOINC display name : HLA-DRB1 SBT High resolution Nom (Specimen);
LOINC long common name : HLA-DRB1 SBT [Type] in Specimen by High resolution;
LOINC short name : HLA-DRB1 SBT Spec High Res;
LOINC description : HLA-DRB typing identifies HLA allelic polymorphism using DNA amplified by Polymerase
Chain Reaction(PCR). HLA typing is vital for bone marrow transplantation. Well-matched
donors increase patient survival and decreases incidence of graft vs.host disease.
HLA-DRB1 sequence typing is used to identify unrelated allogeneic bone marrow donors
who are HLA-DRB genotypic matches to the recipient. For DRB1, the allelic variability
is mainly in the second exon, clustered in three distinct regions that show variance.
If fewer than two alleles is reported for a locus, the patient is likely to be homozygous
for that locus, but the possibility of the presence of rare alleles exists. Information
from ARUP Laboratories 2007 07 17.;
Has component