LOINC long common name : Lupus anticoagulant neutralization dilute phospholipid [Time] in Platelet poor plasma;
LOINC short name : LA Nt dPL PPP;
LOINC description : A modified prothrombin time is performed using diluted thromboplastin reagent which
lowers the phospholipid concentration, which optimizes sensitivity to Lupus Anticoagulants
(LA). Standard prothrombin tests are usually normal in patients with lupus anticoagulants
because of the high concentration of phospholipids in normal thromboplastin reagent.
Lupus anticoagulants are antibodies which inhibit the coagulation results of phospholipid-dependent
tests including APPT, KCT,dRVVT, and dPT. The dPT test screens for the phospholipid-dependent
inhibitors of the extrinsic pathway of the coagulation cascade. Information from PA
Labs, LLC-Midwest Coag (personal communication) and www.labcorp.com, accessed 2008
02 28.;
Has component