Glial nuclear type 1 Ab:Titr:Pt:CSF:SemiQn: - CISMeF
Glial nuclear type 1 Ab:Titr:Pt:CSF:SemiQn:LOINC code
Preferred Label : Glial nuclear type 1 Ab:Titr:Pt:CSF:SemiQn:;
LOINC status : ACTIVE;
LOINC display name : Glial nuclear type 1 Ab (CSF) [Titer];
LOINC long common name : Glial nuclear type 1 Ab [Titer] in Cerebral spinal fluid;
LOINC short name : Glial nuc type 1 Ab Titr CSF;
LOINC description : Glial Nuclear Antibody Antibody (AGNA) Type 1 Cerebrospinal Fluid (CSF) Titer. This
antibody is a marker found in paraneoplastic syndrome associated with small cell lung
carcinoma (SCLC). It is also closely associated with paraneoplastic Lambert-Easton
Myasthenia Syndrome (LEMS). There appears to be a tight association between AGNA and
voltage-gated calcium channel antibodies in patients with SCLC. Patients with AGNA
have characteristic nuclear staining of the Bergmann glia in the Purkinje cell layer
of the cerebellum. Information from Paraneoplastic Limbic encephalitis associated
with potassium channel antibodies: value of anti-glial nuclear antibodies in identifying
the tumour by L. Zuliani, A. Saiz, B. Tavolato, B. Giometto, A. Vincent and Francesc
Graus, JNNP m 2007; 78; p. 204-205.;