Neuronal nuclear type 2 Ab:Titr:Pt:CSF:SemiQn: - CISMeF
Neuronal nuclear type 2 Ab:Titr:Pt:CSF:SemiQn:LOINC code
Preferred Label : Neuronal nuclear type 2 Ab:Titr:Pt:CSF:SemiQn:;
LOINC status : ACTIVE;
LOINC display name : Neuronal nuclear type 2 Ab (CSF) [Titer];
LOINC long common name : Neuronal nuclear type 2 Ab [Titer] in Cerebral spinal fluid;
LOINC short name : Hu2 Ab Titr CSF;
LOINC description : Antineuronal Nuclear Antibody (ANNA) Type 2 Cerebrospinal Fluid (CSF) Titer. This
antibody recognizes a set of protein antigens of 55 and 80 kD found in neuronal cell
nuclei. Patients usually present with signs of midbrain, brain stem, cerebellar and/or
spinal cord dysfunction. Ocular opsoclonus-myoclonus may be a symptom. Para neoplastic
opsoclonus, which is characterized by involuntary rapid movement of the eyes in both
vertical and horizontal planes, is most often associated with breast cancer and SCLC
(small lung cell carcinoma). The autoantibody has also been detected in patients with
bladder and cervical cancer. Paraneoplastic syndromes are autoantibody-mediated neurologic
disorders associated with underlying tumors. These syndromes arise when systemic tumors
express antigens normally found only in neural tissues. Information from http://www.clinlabnavigator.com
accessed 2008 14 02.;