LOINC display name : Platelet aggregation arachidonate induced Qn (PRP);
LOINC long common name : Platelet aggregation arachidonate induced [Units/volume] in Platelet rich plasma;
LOINC short name : PA AA PRP-aCnc;
LOINC description : A whole blood assay for detecting platelet inhibition or dysfunction due to aspirin
therapy. This in vitro assay uses citrated whole blood in the point of care or laboratory
setting. Not for use in patients with underlying congenital platelet abnormalities,
patients with non-aspirin induced acquired platelet abnormalities or in patients receiving
non-aspirin platelet agents (may be used in patients treated with COX-2 inhibitors,
e.g., (Celebrex(r))). The VerifyNow assay incorporates the agonist arachidonic acid
to activate platelets, and measures platelet function based upon the ability of activated
platelets to bind fibrinogen. Fibrinogen-coated microparticles aggregate in whole
blood in proportion to the number of unblocked platelets GP IIb/IIIa receptors. Light
transmittance increases in as activated platelets bind and aggregate fibrinogen-coated
beads. The instrument measures this change in optical signal caused by aggregation.
Information from VerifyNow Aspirin Assay package insert from www.Accumetrics.com accessed
2090618.;
Has component