LOINC display name : IgG clearance/Albumin clearance (S CSF) [Ratio];
LOINC long common name : IgG clearance/Albumin clearance [Ratio] in Serum and CSF;
LOINC short name : IgG/Alb clear Ser CSF-Rto;
LOINC description : Ratio of a patient's IgG and albumin in CSF to the IgG and albumin in serum is of
diagnostic value in a number of neurological disorders. Normally CSF albumin and IgG
are derived from the serum, whereas in patients with active multiple sclerosis, the
increased CSF IgG is believed to be synthesized within the CSF. The CSF Index is a
calculated value which expresses the ratio of IgG to albumin in CSF, to the ratio
of IgG to albumin in serum. An elevated ratio suggests local CNS synthesis of IgG.
An increased CSF/IgG Index is found in diseases such as MS, neurosyphilis, subacute
sclerosing panencephalitis (SSPE), chronic CNS infections and CNS lupus erythematosus.;
Has component