Preferred Label : synchronization (principle of nonperfect synchronization);
IUPAC definition : This principle applies to reactions in which there is a lack of synchronization between
bond formation or bond rupture and other primitive changes that affect the stability
of products and reactants, such as resonance, solvation, electrostatic, hydrogen bonding
and polarizability effects. The principle states that a product-stabilizing factor
whose development lags behind bond changes at the i transition state /i , or a reactant-stabilizing
factor whose loss is ahead of bond changes at the transition state, increases the
intrinsic barrier and decreases the 'intrinsic rate constant' of a reaction. For a
product-stabilizing factor whose development is ahead of bond changes, or reactant
factors whose loss lags behind bond changes, the opposite relations hold. The reverse
effects are observable for factors that destabilize a reactant or product.;
Origin ID : S06218;
UMLS CUI : C0439580;
Currated CISMeF NLP mapping
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
This principle applies to reactions in which there is a lack of synchronization between
bond formation or bond rupture and other primitive changes that affect the stability
of products and reactants, such as resonance, solvation, electrostatic, hydrogen bonding
and polarizability effects. The principle states that a product-stabilizing factor
whose development lags behind bond changes at the i transition state /i , or a reactant-stabilizing
factor whose loss is ahead of bond changes at the transition state, increases the
intrinsic barrier and decreases the 'intrinsic rate constant' of a reaction. For a
product-stabilizing factor whose development is ahead of bond changes, or reactant
factors whose loss lags behind bond changes, the opposite relations hold. The reverse
effects are observable for factors that destabilize a reactant or product.
