Preferred Label : Swain–Scott equation;
IUPAC definition : The linear free-energy relation of the form: \[\log _{10}(\frac{k}{k_{0}}) s\ n\]
applied to the variation of reactivity of a given electrophilic substrate towards
a series of nucleophilic reagents. n is characteristic of the reagent (i.e. a measure
of its nucleophilicity) and s is characteristic of the substrate (i.e. a measure of
its sensitivity to the nucleophilicity of the reagent). A scale of n values is based
on the rate coefficients k for the reaction of methyl bromide with nucleophiles in
water at 25 C, s being defined as 1.00 for these reactions and n being defined as
0.00 for the hydrolysis of methyl bromide. (Other scales have been devised.);
Origin ID : S06201;
See also
The linear free-energy relation of the form: \[\log _{10}(\frac{k}{k_{0}}) s\ n\]
applied to the variation of reactivity of a given electrophilic substrate towards
a series of nucleophilic reagents. n is characteristic of the reagent (i.e. a measure
of its nucleophilicity) and s is characteristic of the substrate (i.e. a measure of
its sensitivity to the nucleophilicity of the reagent). A scale of n values is based
on the rate coefficients k for the reaction of methyl bromide with nucleophiles in
water at 25 C, s being defined as 1.00 for these reactions and n being defined as
0.00 for the hydrolysis of methyl bromide. (Other scales have been devised.)
