Preferred Label : pro-R, pro-S;
IUPAC definition : A stereoheterotopic group c (as in tetrahedral Xabc sub 2 /sub ) is described as
i pro-R /i if, when it is arbitrarily assigned CIP priority over the other stereoheterotopic
group c, the configuration of the thus generated chiral centre is assigned the stereodescriptor
i R /i . The other group c is then described as i pro-S /i . This method for distinguishing
between stereoheterotopic groups can be applied to other kinds of prochiral molecular
entities or prochiral parts of molecular entities considered on their own.;
Origin ID : P04889;
Automatic exact mappings (from CISMeF team)
- See also
A stereoheterotopic group c (as in tetrahedral Xabc sub 2 /sub ) is described as
i pro-R /i if, when it is arbitrarily assigned CIP priority over the other stereoheterotopic
group c, the configuration of the thus generated chiral centre is assigned the stereodescriptor
i R /i . The other group c is then described as i pro-S /i . This method for distinguishing
between stereoheterotopic groups can be applied to other kinds of prochiral molecular
entities or prochiral parts of molecular entities considered on their own.
