Preferred Label : photoaffinity labelling;
IUPAC acronym : PAL;
IUPAC definition : Technique by which a photochemically reactive molecular entity, specifically associated
with a biomolecule, is photo-excited in order to covalently attach a label to the
biomolecule, usually via intermediates. Identification of the resulting photo-crosslinked
product provides structural information on the protein′s binding site.;
Scope note : typical examples are nitrenes, carbenes, ketone excited states, cations and radicals.; technique widely used for identifying in general ligand-receptor interactions in biological
macromolecules and in particular the binding site within proteins.;
Origin ID : P04578;
Automatic exact mappings (from CISMeF team)
- See also
- See also inter- (CISMeF)
Technique by which a photochemically reactive molecular entity, specifically associated
with a biomolecule, is photo-excited in order to covalently attach a label to the
biomolecule, usually via intermediates. Identification of the resulting photo-crosslinked
product provides structural information on the protein′s binding site.
