IUPAC definition : Lipophilicity represents the affinity of a molecule or a moiety for a lipophilic environment.
It is commonly measured by its distribution behaviour in a biphasic system, either
liquid-liquid ( i e.g /i ., partition coefficient in 1-octanol/water) or solid-liquid
(retention on reversed-phase high-performance liquid chromatography ( i RP-HPLC /i
) or thin-layer chromatography ( i TLC /i ) system).;
Lipophilicity represents the affinity of a molecule or a moiety for a lipophilic environment.
It is commonly measured by its distribution behaviour in a biphasic system, either
liquid-liquid ( i e.g /i ., partition coefficient in 1-octanol/water) or solid-liquid
(retention on reversed-phase high-performance liquid chromatography ( i RP-HPLC /i
) or thin-layer chromatography ( i TLC /i ) system).