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Preferred Label : ipso-attack;

IUPAC definition : The attachment of an entering group to a position in an aromatic compound already carrying a substituent group (other than hydrogen). The entering group may displace that substituent group but may also itself be expelled or migrate to a different position in a subsequent step. The term ' i ipso /i -substitution' is not used, since it is synonymous with substitution. For example: where E is an electrophile and Z is a substituent (other than hydrogen).;

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The attachment of an entering group to a position in an aromatic compound already carrying a substituent group (other than hydrogen). The entering group may displace that substituent group but may also itself be expelled or migrate to a different position in a subsequent step. The term ' i ipso /i -substitution' is not used, since it is synonymous with substitution. For example: where E is an electrophile and Z is a substituent (other than hydrogen).

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17/06/2025


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