Preferred Label : feed-back inhibition;
Detailed label : feed-back inhibition (end product inhibition) in biotechnology;
IUPAC definition : A metabolic control mechanism in which the end product of a biochemical sequence is
able to inhibit the activity of an early enzyme in the sequence, thereby controlling
the metabolic flux through this pathway. As an example, isoleucine controls its own
synthesis by inhibiting threonine deaminase; adenosine 5-triphosphate (ATP) and citrate
control glycolysis by inhibiting phosphofructokinase.;
Origin ID : F02333;
See also
A metabolic control mechanism in which the end product of a biochemical sequence is
able to inhibit the activity of an early enzyme in the sequence, thereby controlling
the metabolic flux through this pathway. As an example, isoleucine controls its own
synthesis by inhibiting threonine deaminase; adenosine 5-triphosphate (ATP) and citrate
control glycolysis by inhibiting phosphofructokinase.
