Preferred Label : denaturation;
Detailed label : denaturation of a macromolecule;
IUPAC definition : The process of partial or total alteration of the native structure of a macromolecule
resulting from the loss of tertiary or tertiary and secondary structure that is a
consequence of the disruption of stabilizing weak bonds. Denaturation can occur when
proteins and nucleic acids are subjected to elevated temperature or to extremes of
pH, or to non-physiological concentrations of salt, organic solvents, urea or other
chemical agents.;
Origin ID : D01586;
Automatic exact mappings (from CISMeF team)
- See also
The process of partial or total alteration of the native structure of a macromolecule
resulting from the loss of tertiary or tertiary and secondary structure that is a
consequence of the disruption of stabilizing weak bonds. Denaturation can occur when
proteins and nucleic acids are subjected to elevated temperature or to extremes of
pH, or to non-physiological concentrations of salt, organic solvents, urea or other
chemical agents.
