Preferred Label : comparative molecular field analysis;
Detailed label : comparative molecular field analysis (CoMFA);
IUPAC acronym : 3D-QSAR; CoMFA;
IUPAC definition : Comparative Molecular Field Analysis (CoMFA) is a 3D-QSAR method that uses statistical
correlation techniques for the analysis of the quantitative relationship between the
biological activity of a set of compounds with a special alignment, and their three-dimensional
electronic and steric properties. Other properties, such as hydrophobicity and H-bonding,
can also be incorporated into the analysis.;
Origin ID : CT06951;
Automatic exact mappings (from CISMeF team)
- See also
Comparative Molecular Field Analysis (CoMFA) is a 3D-QSAR method that uses statistical
correlation techniques for the analysis of the quantitative relationship between the
biological activity of a set of compounds with a special alignment, and their three-dimensional
electronic and steric properties. Other properties, such as hydrophobicity and H-bonding,
can also be incorporated into the analysis.
