Preferred Label : clearance;
Detailed label : clearance in toxicology;
IUPAC definition : renal toxicology quantification of the removal of a substance by the kidneys by the
processes of filtration and secretion; clearance is calculated by relating the rate
of renal excretion to the plasma concentration.; pulmonary toxicology volume or mass of lung cleared divided by time of elimination;
used qualitatively to describe removal of any inhaled substance which deposits on
the lining surface of the lung.; volume of blood or plasma or mass of an organ effectively cleared of a substance by
elimination (metabolism and excretion) divided by time of elimination.;
Scope note : total clearance is the sum of the clearances of each eliminating organ or tissue for
a given substance.;
Origin ID : CT06860;
Automatic exact mappings (from CISMeF team)
- See also
renal toxicology quantification of the removal of a substance by the kidneys by the
processes of filtration and secretion; clearance is calculated by relating the rate
of renal excretion to the plasma concentration.
pulmonary toxicology volume or mass of lung cleared divided by time of elimination;
used qualitatively to describe removal of any inhaled substance which deposits on
the lining surface of the lung.
volume of blood or plasma or mass of an organ effectively cleared of a substance by
elimination (metabolism and excretion) divided by time of elimination.
